Abstract

Kaposi's sarcoma (KS) is a low-grade vascular tumor, with four main variants, one of which is fairly prevalent in HIV-infected patients. Mucocutaneus and lymph node involvement is characteristic. The gastrointestinal tract is involved in 40% of patients, but rectal and anal canal involvement is exceptional. We report the case of a 39-year-old HIV-infected man with an unusual presentation of KS with colorectal and anal canal involvement in the absence of cutaneous disease. The patient was treated with highly active antiretroviral therapy and systemic chemotherapy, with partial response. Local radiation therapy of the rectum produced local remission.

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