Abstract
PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis) is the most common periodic fever in childhood. It is a benign self-limiting condition that may resolve spontaneously during the first years of life or within adolescence, although there is increasing evidence of cases that may persist also in adulthood. A small dose of corticosteroids is safe and effective for the management of fever episodes and can also be useful for the diagnosis. Tonsillectomy is a good option for those patients who keep presenting with disabling symptoms after the typical age.
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