Saponins from leaves of Acanthopanax senticoshs Harms., Ciwujia. II. Structures of ciwujianosides A1, A2, A3, A4 and D3.

Abstract

Further investigation of the chemical constituents of the leaves of Acanthopanax senticosus HARMS. resulted in the isolation of five new triterpenoid saponins, named ciwujianosides A1 (1), A2 (2), A3 (3), D3(4) and A4 (5). The structures of these saponins were elucidated as follows : 1, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosyloleanolic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 2, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosyl-30-norolean-12, 20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 3, 3-O-α-rhamnopyranosyl-(1→2)-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 4, 3-O-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-6-O-acetyl-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 5, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-6-O-acetyl-β-glucopyranosyl-(1→6)-β-glucopyanosyl ester.