Abstract
A new 19-oxa-tricyclohenicosatetraenone and a new dioxacyclopropacycloundecene-10-carboaldehyde and its 6,7-dihydro derivative, named saponaroxins A–C, were isolated from the culture filtrate of Alternaria saponariae a fungal pathogen of the well-known medicinal plant Saponaria officinalis. Saponaroxins A–C were characterized by spectroscopic methods. When assayed on punctured leaf segments of two weeds, Sonchus arvensis and Elytrigia repens saponaroxins B–C were found to be phytotoxic. They demonstrated moderate antimicrobial activity and low toxicity against Paramecium caudatum. Saponaroxin A was acutely toxic to P. caudatum while showed no phytotoxic nor antimicrobial activity.
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