Abstract

This is a review article on how we can sample the COVID-19 patients, what samples can be obtained, what are the procedures to collect those samples and the precautions some laboratory personnel need to take while processing the samples. This review article mainly focuses on the various methods used in India while sampling COVID-19 patients. For now, RT-PCR is the most reliable test for COVID-19 detection.

Highlights

  • This is a review article on how we can sample the COVID-19 patients, what samples can be obtained, what are the procedures to collect those samples and the precautions some laboratory personnel need to take while processing the samples

  • This review article mainly focuses on the various methods used in India while sampling COVID-19 patients

  • COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2)

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Summary

Background

COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). Other names of COVID-19 are 2019-nCoV acute respiratory disease, Novel coronavirus [1,2,3,4,5,6,7,8]. Nucleic acid detection is the gold standard for diagnosis of coronavirus disease 2019, and the nasopharyngeal swab is the main method of sampling. This test shows > 94.7% sensitivity and > 98.6% specificity. Special rooms have been designed for nasopharyngeal swab sampling which reduces the risk for health workers [12] (Figure 1).

Nasopharyngeal wash specimen
Methods of Specimen Collection

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