Abstract
Background: SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) is both a dermatological and a rheumatological entity, with the common denominator of an aseptic inflammatory process, the bone manifestations of which are the essential element of the diagnosis. Despite its chronic and recurrent nature, SAPHO syndrome is very rarely the cause of major disability, even after several decades of evolution. Objective: We want to illustrate through three clinical cases, the importance of the anamnesis, the clinic, the diagnostic criteria in the diagnosis of SAPHO syndrome. Presentation of the cases: We studied the clinical file of three patients consulted in the Rheumatology Department of the CHU Aristide LeDantec in Dakar, Senegal, between January 2012 and December 2020, suffering from SAPHO syndrome of diagnosis established in accordance with the diagnostic criteria of SAPHO syndrome proposed by Khan et al. of 1994. Conclusion: SAPHO syndrome is a rare pathological entity, over a period of 8 years we report 3 cases.
Highlights
SAPHO syndrome is referred to as “Skibo-disease”, which is a combination of bone and joint manifestations related to dermatologic signs [1], as defined by Kahn et al in 1994 [2]
Presentation of the cases: We studied the clinical file of three patients consulted in the Rheumatology Department of the CHU Aristide LeDantec in Dakar, Senegal, between January 2012 and December 2020, suffering from SAPHO syndrome of diagnosis established in accordance with the diagnostic criteria of SAPHO syndrome proposed by Khan et al of 1994
The methodology was the study of the clinical file of three patients consulted in the rheumatology department of the CHU Aristide LeDantec in Dakar, Senegal, between January 2012 and December 2020, suffering from SAPHO syndrome of diagnosis established in accordance with the diagnostic criteria of SAPHO syndrome proposed by Khan et al of 1994
Summary
SAPHO syndrome is referred to as “Skibo-disease” (short for skin-bone), which is a combination of bone and joint manifestations related to dermatologic signs [1], as defined by Kahn et al in 1994 [2]. The epidemiological data available do not allow us to estimate its prevalence due to the lack of a precise census of proven cases. It is a painful and disabling disease that affects women more frequently than men, and especially young adults between 30 and 50 years of age [3]. The diagnostic criteria for SAPHO syndrome proposed by Kahn et al in 1994 are 3: 1) aseptic mul-
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