SAPHENOUS VEIN GRAFT PATENCY AFTER GEOMETRY REMODELING

Abstract

Tortuous saphenous vein graft (SVG) hemodynamics was investigated using computational fluid dynamics (CFD) techniques. Computed tomography (CT) technology is used for noninvasive bypass graft assessment seven days after surgery. CT investigation shows two regions with severe shape remodeling, one is an angle type contortion and the other one is a sharp curvature with tortuous area reduction. The numerical analysis carefully examines the effect of an SVG geometry remodeling through flow separation, particle deposition, and wall shear stress (WSS). During the cardiac cycle, overall pressure drop increases from 2.6[Formula: see text]mmHg to 4.4[Formula: see text]mmHg. In the accelerating part of the systolic phase, particles released in the inlet section move downstream toward the first narrowed part (elbow type contortion) with a helical motion. WSS range along the cardiac cycle varies from 2[Formula: see text]Pa to 42[Formula: see text]Pa, enough to damage the endothelial cells. Vessel torsion induced helical flow can reduce the flow disturbance and separation. Additionally, in the distal end of the graft, the high particle concentrations can promote the inflammatory processes in the vessels.