Sanger sequencing versus INNO-LiPA® HBV PreCore assay for routine detection of precore and basal core promoter mutations in hepatitis virus B chronically infected patients

E.K Alidjinou,L Bocket,V Pigot,V Lambert,C Hallaert,V Canva,D Hober

doi:10.1016/j.diagmicrobio.2017.12.006

Sanger sequencing versus INNO-LiPA® HBV PreCore assay for routine detection of precore and basal core promoter mutations in hepatitis virus B chronically infected patients

E.K Alidjinou, L Bocket + Show 5 more

https://doi.org/10.1016/j.diagmicrobio.2017.12.006

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Journal: Diagnostic Microbiology & Infectious Disease	Publication Date: Dec 17, 2017
Citations: 2

Affiliation: University of Lille, Centre Hospitalier Universitaire de Lille

#Basal Core Promoter Mutations #Precore Mutations + Show 8 more

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Abstract

We compared the Sanger sequencing and the commercial INNO-LiPA® HBV assay for the routine detection of precore (PC) and basal core promoter (BCP) mutations of hepatitis B virus in chronically infected patients. The overall agreement rate between assays was 94.2% and 98.8% for the detection of PC and BCP mutations, respectively.

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