Abstract
A review is given of the extraction and purification of biological samples by filtration through lipophilic neutral and ion-exchange dextran gels and their derivatives. Liquid-gel extraction, reversed-phase liquid chromatography and ligand-exchange chromatography are also discussed. The applications of Sepfhadex and Lipidex gels are reviewed, with special reference to extractions from biological fluids and solid samples and the extraction of metabolites. A number of selective isolation procedures are reviewed for estrogens, lignans, isoflavanes, isoflavones, catechol estrogens, ketonic compounds and ethynyl steroids.
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