Salviae miltiorrhizae and ligustrazine injection combined with tiotropium bromide in treatment of chronic obstructive pulmonary disease

Abstract

Objective To investigate the clinical effect of salviae miltiorrhizae and ligustrazine injection combined with tiotropium bromide in the treatment of chronic obstructive pulmonary disease. Methods 110 patients with chronic obstructive pulmonary disease treated at our hospital from January, 2015 to May, 2017 were chosen as experimental subjects, and were divided into a control group and a research group, 55 for each group. Both groups were routinely treated; in addition, the control group were treated with tiotropium bromide, and research group with tiotropium bromide and salviae miltiorrhizae and ligustrazine injection. After the treatment, the clinical effects, pulmonary function, blood gas indexes, and adverse reactions were compared between two group. Results The cured rate was 18.18%, the excellence rate 67.27%, and the effective rate was 14.54% in the research group, which were better than those in the control group, with statistical differences (P 0.05). There were no statistical differences in pulmonary function indicators between the two groups before the treatment (P>0.05). After the treatment, the pulmonary function indicators were better in the research group than in the control group, with statistical differences (P 0.05). Conclusion Salviae miltiorrhizae and ligustrazine injection combined with tiotropium bromide in the treatment of chronic obstructive pulmonary disease is effective and safe and can improve the patients’ pulmonary function, so it is worth being clinically generalized. Key words: Chronic obstructive pulmonary disease; Salviae miltiorrhizae and ligustrazine; Tiotropium bromide; Pulmonary function