Abstract
We demonstrated that the fine control over the surface charge density of chemically converted-graphene (CCG) is possible via salt “invasion”, resulting in the formation of self-assembled stacked-CCG colloids in solution, which can serve as powerful building blocks for the capturing of DNAs independent of their structure that are not available to traditional colloidal graphene-based materials, thus providing our new insight into graphene/DNA interaction. Furthermore, the self-assembled bio-composites exhibit high stability even in saline solution (0.4 M NaCl) and can function as ideal components for real-time assay for screening genotoxic chemicals, not only avoiding the complex layer-by-layer assembly in comparison with those of conventional electrochemistry-based sensors, but also improving the signal transduction. We envision that the stacked-CCG, a novel type of colloidal graphene-derived material, could open new opportunities for the rational design of multifunctional graphene-based biocomposites and provide a brand new avenue in biosensing, drug screening and genotoxicity screening in the future.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
