Salt and Cardio-Renal Connection

Abstract

In all animal models examined whose blood pressure (BP) is sensitive to changes in salt intake, glomerular BP indeed proved elevated. In fact, we quantitatively estimated glomerular BP elevated in this type of hypertension. We also showed that BP failed to fall during night in patients with salt sensitive type of hypertension, and they manifested as non-dippers. In addition, high cardiovascular event rates were recognized in salt sensitive patients than in non-salt sensitive patients.