Abstract
Salmophage® is a new preparation developed against salmonellosis in fowl. It has two components : a dry live vaccine and a bacteriophage. Unlike conventional vaccines which trigger solely an active immune response against the vaccine strain, Salmophage® also has a therapeutic effect due to its phage component. Experimental inoculation in white mice and chicken demonstrated that Salmophage ® is more effective as a preventive agent that the conventional vaccine, especially when Salmonella contamination occurs at a time when animals are unable to develop an active immunity. Therefore, the phage component of the preparation can prevent the death of chicks heavily contaminated just a few days after hatching. A preliminary investigation in Salmonella-infected chicken showed that Salmophage® improves animal survival and helps produce poultry products free of Salmonella enteritidis.
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