Sağlık Taraması İçin Başvuran Hastane Personelinde Serum HbsAg ve Anti-Hbs Düzeyleri İle Hepatit B Aşılanma Durumu

Abstract

Objective: This study was performed to research the HBsAg and anti-HBs levels with the hepatitis B vaccination status in hospital staff admitted to family medicine outpatient clinic for health screening. Method: This descriptive study was being carried out in 519 hospital health staff admitted to family medicine outpatient clinic for health screening between 03.10.2015 and 30.12.2015. Socio-demographic characteristics and hepatitis B vaccination status of the participants were recorded on forms prepared in advance by researchers. Serum HBsAg and anti-HBs levels were measured. Antibody titers of 10 and below were considered negative and these staff were taken to 3 doses of hepatitis B vaccine program. Results: Of the participants, 35.6% (n=185) were female, 64,4% (n=334) were male and the mean age was 35.24 ± 8.35 years. One hundred and sixty-two (31.2%) had 0-10 mIU/ml, 14.5% (n=75) had 10-100 mIU/mL levels, 54.3% (n=282) ≥100 mIU/mL of the anti-HBsAg value. The serum HBsAg levels of the hospital staff were found as 97.7% (n=507) negative and 2.3% (n=12) positive. While there was no statistically significant difference between the gender and serum HBsAg levels, a statistically significant difference was found between the ages of the staff and serum HBsAg levels (p<0,001). Conclusion: Hepatitis B virus (HBV) is a pathogen that is at risk of health care workers. All health care workers at risk should be immunized against hepatitis B virus. One of the most effective methods in the prevention of hepatitis B infection was immunization. In this study, 68.8% were seropositivite and 2.3% were hepatitis B carriers in accordance with other studies in Turkey. Key words: Health staff, screening, hepatitis B vaccine, anti-HBs, HBs Ag. Amac: Bu calisma, saglik taramasi icin aile hekimligi poliklinigine basvuran hastane personelinde serum HBsAg ve anti-HBs duzeyleri ile, hepatit B asilanma durumlarini arastirmak icin yapilmistir. Yontem: Tanimlayici tipteki bu arastirma, 03.10.2015-30.12.2015 tarihleri arasinda, saglik taramasi icin poliklinigimize basvuran 519 hastane personelinde yapilmistir. Katilimcilarin sosyodemografik ozellikleri ve hepatit B asilanma durumlari, arastirmacilar tarafindan onceden hazirlanan formlara kaydedilmistir. Serum HBsAg ve anti-HBs duzeyleri olculdu. Antikor titresi 10 mIU/mL ve altindaki degerler negatif olarak kabul edildi ve bu personeller 3 doz Hepatit B asi programina alinmistir Bulgular: Katilimcilarin %35,6’si (n=185) kadin, %64,4’u (n=334) erkek, yas ortalamasi 35,24±8,35 yil idi. Yuz altmis iki kiside (%31,2) anti-HBs duzeyi 0-10 mIU/mL arasinda, %14,5’inde (n=75) 10-100 mIU/mL arasinda, %54,3’unde (n=282) ≥100 mIU/mL idi. Serum HBsAg duzeyi, hastane personelinin %97.7’sinde (n=507) negatif, % 2.3’unde (n=12) pozitif bulundu. HBsAg pozitifliginin cinsiyetle degil, yasla anlamli farklilik gosterdigi tespit edilmistir (p<0,001). Sonuc: Hepatit B virusu (HBV), hastane calisanlarinin risk altinda oldugu bir patojendir ve tum hastane personeli hepatit B virusune karsi bagisik olmalidir. Hepatit B enfeksiyonundan korunmada en etkili yontem asilamadir. Bu calismada bulunan % 68,8 oraninda antikor titresi pozitifligi ve % 2,3 oraninda hepatit B tasiyiciligi, ulkemizde yapilan diger calismalarla uyumludur. Anahtar kelimeler: Hastane personeli, tarama, hepatit B asisi, anti-HBs, HBsAg.