Abstract
Salivary glucose levels, oral candidal carriage, candidal strain diversity and antifungal susceptibility of candida among adult diabetic patients
Highlights
Diabetes Mellitus is a clinical syndrome characterised by hyperglycemia due to absolute or relative deficiency of insulin
Salivary glucose levels were significantly higher in diabetics and there was significant correlation between salivary glucose and random non-fasting plasma glucose
The antifungal susceptibility revealed that the Candida had different rates of resistance to the tested antifungal drugs except Amphotericin B
Summary
90 subjects with age range of 40-60 years were selected. Diabetic status was determined by estimation of random non-fasting plasma glucose levels and glycosylated hemoglobin levels. Un-stimulated and stimulated saliva was analyzed for glucose levels. An oral rinse sample with Phosphate buffered saline was used to assess candidal colonization. The candidal isolates were identified and tested for in-vitro antifungal susceptibility using disc diffusion method
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