Abstract
Luteal support effect in IVF has been evaluated by measurement of serum progesterone (1) and the effect of progesterone on the endometrium (2). Intramuscular hCG treatment produces higher serum progesterone concentrations than does vaginally administered micronized progesterone, which produces higher and longer-sustained plasma progesterone levels than the same oral dose. Salivary progesterone measurement can be used for longitudinal monitoring of luteal function (3), and it displays both free and total serum progesterone levels during normal menstrual cycle and in pregnancy. During a normal menstrual cycle, salivary progesterone levels are 0.223–0.382 nmol/L (4).
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