Abstract

The simplicity and convenience of collecting saliva, as well as its component composition, make this biological fluid a common object of laboratory research, in particular for detecting the nucleic acids of viruses and bacteria, monitoring certain clinical conditions. The range of clinical situations where to use saliva as a diagnostic tool is becoming increasingly widespread and also includes determination of secretory status. The aim of this paper is to characterize the secretory status of the oral fluid, depending on the presence of group-specific antigens of the AB0 system.

Highlights

  • Constancy of internal environment of an organism is a necessary condition for normal functioning and vital activity of all its systems

  • The objective of this study is to characterize the secretory status of oral fluid depending on the presence of groupspecific antigens according to the AB0 system

  • Conclusion a) For the first time we used the Vidas technique to determine the secretory status of oral fluid by A and B antigens

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Summary

Introduction

Constancy of internal environment of an organism is a necessary condition for normal functioning and vital activity of all its systems. For the first time the term “histo-hematic barrier” was used in 1929 by the Soviet scientist L.S. For the first time the term “histo-hematic barrier” was used in 1929 by the Soviet scientist L.S Stern who defined it as a plastic, mobile mechanism taking part in maintaining the constancy of the internal environment and function, which can be regulated by exogenous and endogenous biologically active substances [1]. By means of histo-hematic barriers the passage of electrolytes, proteins with small molecular weight, products of metabolism, factors of specific and non-specific protection from blood to tissue fluid is carried out, which promotes breathing, trophism, cells proliferation and differentiation, elimination of unnecessary components formed during metabolism from organs and tissues [2]. Hemato-encephalic (blood–brain barrier), hematoplacental, hemato-ophthalmic (blood–ocular barrier), and hematosalivary barriers are distinguished by their localization [3]

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