SALIVA AS A DIAGNOSTIC TOOL-A REVIEW

Abstract

Early perseverance of disease plays the important part of treatment planning and prognosis which reduces the severity of disease progression. This scrutiny explains the saliva as a fascinating diagnostic tool for routine examination of identifying the oral and systemic disease in its early stage. On upper hand, saliva includes uncluttering and non-invasive method with trouble free method of collecting the sample with low-cost storage. Whole saliva may be used for diagnosis of systemic and oral disease because it contains serum constituents which serve as accurate biomarkers for the diagnosis of disease. Saliva samples are easy to store and ship as it doesn't clot similar to blood. Saliva present in the oral cavity not only maintains the health of oral cavity but plays an important role in diagnosis of communicable and non-communicable disease. No need for trained medical staff, Multiple samples can be obtained easily, Collection and screening can be done at home Minimal risks of cross-contamination, more economical sampling, shipping and storage compared to serum, requires less manipulation during diagnostic procedures compared to serum, Commercial availability of screening assays. All these characteristics make saliva an appealing diagnostic candidate for the detection and monitoring of several biomarkers in infants, children, adults and uncooperative patients.