Saline Infusion Sonogram is Superior to CT Scan for Diagnosis of Osseous Metaplasia

Abstract

Osseous metaplasia refers to formation of bone from a different tissue inside the same individual. In the female genital tract, it mainly occurs in the endometrium, but has been reported in the vagina, in the cervix and in the ovary. The clinical presentation may include menstrual irregularity, pelvic pain, dyspareunia and vaginal discharge, but the one most commonly reported is secondary infertility. Multiple possible pathogenic for the development of osseous metaplasia have been reported, but recent studies could show by DNA analysis that no fetal material was present in endometrial osseous metaplasia, supporting the theory of osseous metaplasia of pluripotent mesenchymal elements.