Abstract

Backround: Breast development, without any signs of sexual maturation, in girls younger than 8 years is almost universally accepted as premature thelarche (PT). Prevalance and etiology are clearly unknown. Objectives: We designed a study to follow up girls who had unilateral or bilateral PT and to show regression after stopping care products. Material and Methods: The design of study was retrospective Children and their parents were enrolled into the study from September 2016 to February 2017. All children had one common symptom which was unilateral or bilateral breast development not associated with pubic or axillary hair, vaginal bleeding or other sign of sexual maturation, at the well child visit. In these children with no organic causes, monitoring was taken after stopping of care products. Result: 28 girls were evaluated and mean age was 2,3 years (± 0,3). Noone had a chronic disease. All cases identified as Tanner stage-2 and continued to have early breast development on follow-up. 18 (64,2%) girls had unilateral breast development. After stopping care products, both group had regression in six months. Conclusions: Currently there are no predictive tests to show the risk of breat development of early or puberty precoccus. Children may be exposed to much more diagnostic tests because of overuse products. Physician must be aware of these products. Families may use a minimum amount of care products for their children.

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