Abstract
Mast cell (MC) disorders (MCDs) are characterized by the proliferation and accumulation of MCs in different tissues, including skin and bone marrow, and/or the inappropriate release of MC mediators, creating symptoms in multiple organ systems. The clinical presentation of MCD is heterogeneous, ranging from a typical rash (urticaria pigmentosa) to a more aggressive systemic variant.1 All MCD patients can experience symptoms of anaphylaxis owing to massive MC activation and the release of mediators.
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Schedule a callMore From: The Journal of Allergy and Clinical Immunology: In Practice
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