Safety assessment of antimicrobials in food packaging paper based on LC-MS method

Dhurgham Ismael Baqer Al Alnabi,Raqad Raheem Al-Hatim,Abduladheem Turki Jalil,Yasser Fakri Mustafa,Sarmad Ghazi Al-Shawi,Zena Kadhim Al-Younis,Asraa Yacoob Yousif

doi:10.1590/fst.68821

Abstract

Many difficulties relating to food safety have been solved thanks to the employment of strong mass spectrometric detectors in conjunction with liquid chromatography. In this study, samples were fractionated using gel permeation chromatography and liquid/liquid extraction, and liquid chromatography/mass spectrometry (LC/MS) and gas chromatography/mass spectrometry were used to detect possible genotoxicant(s) in recycled paperboard. As a genotoxicity indicator, the rec-assay was utilized. Abietic acid (AA) and dehydroabietic acid (DHA) and were discovered in the recycled paperboard to be genotoxic. AA and DHA were found in 2 of 5 virgin products and all seven recycled food-contact products. AA and DHA total levels in virgin goods were 990 and 240 mg/g, respectively, whereas recycled products had 200990 mg/g. The total quantity of AA and DHA content in DNA-damaging activity and paper products were shown to have a strong connection. Furthermore, genotoxic effects in paper products matched standard chemicals well, showing that AA and DHA were primarily responsible for the genotoxic effects of these paper products.

Highlights

Food safety is concerned with the health and well-being of food, which is based on the provision of conditions and methods through which the quality of food is maintained in order to prevent foodborne diseases
We recently studied the genotoxicity of 28 recycled food-contact and virgin goods, concluding that recycled products were more likely to cause DNA damage than virgin products
gel permeation chromatography (GPC) is a technique for determining the molecular weight that is known as size exclusion chromatography

Summary

Introduction

Food safety is concerned with the health and well-being of food, which is based on the provision of conditions and methods through which the quality of food is maintained in order to prevent foodborne diseases. Following a series of widely publicized occurrences all around the world, food safety has earned larger notoriety, including salmonella in peanuts and pistachios in the USA (Casulli et al, 2019), melamine in dairy products from China (Xiu & Klein, 2010), pesticides in soft drinks in India (Erdman et al, 2006; García-Reyes et al, 2008; Johnson et al, 2006), tainted Coca-Cola in Belgium (Johnson & Peppas, 2003), contamination of foods with pesticides in Japan (Maitani, 2004), and France (Nougadère et al, 2012), dioxins in pork and milk products from Belgium (Casey et al, 2010), and beef with bovine spongiform encephalopathy and benzene in carbonated beverages in the United Kingdom (Henson & Mazzocchi, 2002; Kimberlin, 1993) Such events, along with the ongoing debate over genetically modified crops (Kaeppler, 2000), have led to widespread public mistrust of food supplies in many nations. Such as composite paper as the raw material of the paper container, its main types are three kinds

Methods

Results

Conclusion