Safety and Tolerability of Fel d 1-Derived Peptide Antigen Desensitization in Subjects with Controlled Asthma

Abstract

T U E S D A Y 733 The Influences of Low BMI On the Treatment of Fixed Airway Obstruction June-Hyuk Lee, Sung-Woo Park, MD, Dojin Kim, Ansoo Jang, MD; Soonchunhyang univ bucheon hospital, Soonchunhyang Univ. Hospital, Bucheon, Soon Chum Hyang University Hospital, Bucheon. RATIONALE: Body mass index(BMI) has been thought to be associated with development or treatment of obstructive airway disease. HighBMI, so called obesity, was associated with the severity of asthma or extent of emphysematous change. But, it has not been known the effect of low BMI on obstructive lung disease. We tried to evaluate the influence of low BMI on fixed airway obstruction. METHODS: 245 patients with fixed airway obstruction were enrolled. The levels of BMI of all subjects were less than 18. Subjects were classified into grade according to FEV1. RESULTS: Absolute values of BMI were significantly associated with the degree of airway obstruction and also significantly associated with lung function. The subjects who have high grade of fixed airway obstruction showed significantly more frequent(P 5 0.02) and longer duration of hospitalizaion(P5 0.007). CONCLUSIONS: Low BMI has an influence on hospitalization for the patient with fixed airway obstruction.