Abstract
Safety and tolerability of anti-diabetic drugs should be among the most concern when it comes to management of Type 2 Diabetes.With the understanding of functions of incretin and degrading enzyme dipeptidepeptidase (DPP-4),several DPP-4 inhibitors with different chemical structures are now available.They are welltolerated with few weight gain,hypoglycemia or adverse effects.Therefore,DPP-4 inhibitors are considered to be among the ideal anti-hyperglycemic agents. Key words: Diabetes mellitus, type 2; DPP-4 inhibitor; Safety
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