Abstract
The purpose of this review is to describe cases of serious neurologic complications due to cervical interlaminar epidural steroid injection, safety techniques to mitigate the risks of these, and briefly cover other more common but less severe complications. The most common complications reported in the largest available cohort of epidural steroid injections include increased pain, steroid side effects, and vasovagal reaction without any cases of serious neurologic complications being captured. The risk of neurologic damage due to aberrant needle location or space occupying lesions is very small, though not zero even if ideal technique is used. Proper utilization of risk mitigation techniques can further reduce the risk of these rare but serious complications.
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