Safety and Efficacy of Trans-radial Approach Compared with Trans-femoral Approach for Coronary Angiography and Coronary Intervention: Real World Experience in Thai Patients

Abstract

between 1 and 17 days following femoral arterial puncture from January 2000 through Febuary 2007, femoral PSAs were treated with UGTI. Bedrest for 4 to 6 h after UGTI was followed by repeat groin duplex scan at 1∼3 days and a clinical follow-up at 30 days. Results: 250 u to 1000 (mean 644.29 u) u of bovine thrombin were injected into the PSA with UGTI. 38 cases were success after a single injection. Incomplete thrombosis was achieved after the first injection 500u thrombin in 2 cases, ultrasound-guided compression(UGC) was successful within 5 minutes. Technical success rate was 100% (40/40), thrombus formation in the superficial femoral artery occurred in 1 patient after successful closure of the PSA, surgical embolectomy was performed. 1 patient had acute allergy after 2min of thrombin injection which was resolved by anti allergic therapy. Clinical success rate was 95%(38/40), reperfusion was detected in 2 patients at 24 h follow-up, 1 patientwas successfullymanagedby a second thrombin injection and another was successfully treated with UGC, recurrence rate of PSA was 5.6%. There is no recurrence at 30days clinical follow up. Conclusions:UGTI is a safe-effectivemethod for the treatment of iatrogenic femoral PSAsandshouldbe considered as first-line therapy. doi:10.1016/j.hlc.2008.05.377