Abstract

BackgroundTazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris.ObjectiveTo review the safety and efficacy studies of tazarotene foam in the treatment of moderate to severe acne.MethodsFive Phase I safety studies in normal controls are reviewed and two Phase III safety and efficacy studies in patients with moderate to severe acne are reviewed.ConclusionTazarotene foam, 0.1% was effective in the treatment of moderate to severe acne vulgaris with an acceptable tolerability profile. This treatment provides a cosmetically favorable alternative for topical retinoid therapy.

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