Safety and Efficacy of Stent-Graft in the Treatment of Aortoiliac Artery Occlusive Disease: A Multicenter Study of Short-Term and Medium-Term Outcomes

Abstract

ObjectiveTo evaluate the short and mid-term safety and efficacy of stent-graft compared with bare stents for treatment of aortoiliac artery occlusive disease (AIOD). Methods183 patients diagnosed with AIOD who received stent implantation at three vascular centers in north China between January 2019 and December 2021 were enrolled. Patients were divided into those undergoing stent-graft (Group A; n=67) or bare stent (Group B; n=116) implantation for retrospective cohort analysis. Efficacy was assessed as surgical success rate and rate of freedom from clinically driven target lesion reintervention (ffCDTLR) at each follow-up time point. Safety was assessed by the rate of perioperative complication, major limb amputation and aortoiliac artery-related mortality. ResultsThere were no preoperative baseline differences between the two groups (p>0.05). The surgical success was 91.04% for Group A, significantly higher than that for Group B (79.31%; p<0.05). Incidence of perioperative complications was 2.98% for Group A, significantly lower than that for Group B (9.48%, p<0.05), as was the rate of major limb amputation (A:1.49% vs B: 5.17%) and aortoiliac artery-related mortality (A: 1.49% vs B: 4.31%), although these two indicators were not significantly different (p>0.05). Follow-up rates were 91.8% for the total follow-up time of 3 years. Kaplan-Meier survival curve analysis gave significantly higher 1- and 2-year ffCDTLR for Group A (98.51% and 95.52%) than for Group B (95.69% and 89.66%, p<0.05). ConclusionStent-graft is more effective and safer than bare stent in the treatment of AIOD