Safety and efficacy of retrograde intrarenal surgery in patients of different age groups

Abstract

ObjectivesTo assess the efficacy and safety of retrograde intrarenal surgery (RIRS) to treat renal stones in different age groups of patients. Patients and methodsWe performed a retrospective analysis of 947 patients who underwent RIRS for renal calculi between January 2008 and January 2014. Age at RIRS was analyzed both as a continuous and categorical variable and patients were categorized into three age groups; aged ≤15 years at surgery (group I, n=51), 16–60 years (group II, n=726) and >60 years (group III, n=170). We compared the 3 groups with the regard to stone characteristics, operative parameters and postoperative outcomes. ResultsThe stone-free rate was 78.4% in group I, 77.5% in group II, and 81.1% in group III (p=.587). A multivariate logistic regression analysis showed that only stone size and stone number had significant influence on the stone-free rates after RIRS. Intraoperative complications occurred 13.7% in group I, 5.6% group II, and 7.6% in group III. Overall complication rates in children were higher than adult patients but the differences were not statistically significant. We found that only operation time was associated with the increased risk of intraoperative complications. Peroperative medical complications developed in 8 patients (.8%) in group II and 2 patients (1.1%) in group III. A 48-year-old man died from septic shock 5 days after the surgery. ConclusionsRIRS was observed to be a safe and effective procedure in all age groups of patients with stone disease, therefore age should not be considered as a limiting factor.