Abstract
Radiofrequency thermal ablation (RFA) can be performed safely and effectively to control local disease in patients with advanced, unresectable liver tumors. Prospective study of 76 patients with unresectable liver tumors who underwent RFA at a private tertiary referral hospital. Ninety-nine RFA operations were performed to ablate 328 tumors. Complications and local recurrence. There was 1 death (1%), major complications occurred in 7 operations (7%), and minor complications occurred in 10 operations (10%). Local recurrence was identified in 30 tumors (9%) at a mean follow-up of 15 months. Size (P<.001), vascular invasion (P<.001), and total volume ablated (P<.001) were associated with recurrence but the number of tumors was not (P =.39). Radiofrequency thermal ablation provides local control of advanced liver tumors with low recurrence and acceptable morbidity.
Highlights
Hypothesis: Radiofrequency thermal ablation (RFA) can be performed safely and effectively to control local disease in patients with advanced, unresectable liver tumors
Hepatocellular carcinoma was diagnosed in 25 patients, colorectal metastases (CRM) in 39 patients, and other metastases in 12 patients
The selection of the RFA approach was individualized after full explanation to each patient of benefits and risks of each approach and informed consent was obtained
Summary
The purpose of this study was to evaluate the safety and efficacy of ultrasound-guided RFA in unresectable liver tumors in patients with more advanced disease
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