Safety and Efficacy of Ferumoxytol as a Lymphatic Contrast Agent

Abstract

Ferumoxytol is a ferromagnetic nanoparticle with lymphotrophic biokinetics. Ferumoxytol is delivered to lymph nodes via normal macrophages. MRI is successful in suppressing normal lymph nodes containing Ferumoxytol. The purpose of this study is to validate this agent's safety and determine its role as a lymph node contrast agent in the prostate cancer population.