Safety and efficacy of corneal cross-linking in children with keratoconus

Abstract

Background: Keratoconus is categorized by advanced corneal protrusion and thinning, important to uneven impairment and astigmatism in ophthalmic purpose, secondary to alter in the arrangement and association of collagen. Objective: This study intended to explain the protection and efficiency of cross-linking corneal for pediatric keratoconus. Materials and Methods: This was a retrospective investigation of 32 eyes of 26 patients, age < 17 years that undertook corneal collagen for advanced keratoconus. Inclusion criteria were progressive keratoconus eyes recognized by successive topography for 6 months. The central significances procedures comprised pachymetry, keratometry, vision, and difficulties following epithelial-off cross-linking with the Dresden procedure. Results: Vernal keratoconjunctivitis (VKC) patients were extra probable to be male; 81.6% of the non-VKC patients and 96.3% of VKC patients were male . Relating pretreatment to the 2-year follow-up, around no statistically substantial modification in the mean sharp or flat keratometry, uncorrected visual acuity (UCVA) and corneal thickness or best spectacle-corrected graphic acuity in either group. There were no statistically substantial modifications in the mean visual, adverse event outcomes between the two groups. The percentage displaying advance of ectasia at 2 years was 18.5% in the VKC group and 16.7% in the non-VKC group (P = 0.83). Conclusions: Cross-linking corneal appears to be protected and active in pausing the advancement of keratoconus in pediatric patients. In addition, it can hypothetically inhibit amblyopia, progress the proper of lenses, and prevent an initial piercing keratoplasty.