Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars

Abstract

ImportanceIt is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. ObjectiveTo identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. Design, setting, and participantsIn this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019. InterventionsAutologous skin tissue cells grafting. Main outcomes and measuresChanges in scar severity, color changes in the scar area, infection rate and patient satisfaction. ResultsA total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%. Conclusions and relevanceIn this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar.