Abstract
Rationale: Treatment with glucagon-like peptide-2 (GLP-2) analogues promotes intestinal adaptation in patients with short bowel syndrome (SBS). Apraglutide is a novel long-acting GLP-2 analogue designed to enable once weekly dosing. This trial investigated the safety and efficacy of once weekly 5 mg apraglutide in patients with SBS intestinal failure (SBS-IF) and intestinal insufficiency (SBS-II).
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