Abstract
An experimental evaluation of anti-fatigue activity of Shramahara Mahaakashaaya (SM) and its applicability in sports medicine has been systematically evaluated. Aqueous, ethanolic and petroleum ether extracts of SM granules (200mg/kg) were studies for light-dark model test for assessment anti-anxiety effect, rota-rod test for assessment of the effect on muscle tone and muscle balance, weight loaded forced swimming test for assessment of anti-fatigue activity. The acute toxicity study of SM granules has also been evaluated as per the OECD 423. SM granules showed significant anti-fatigue activity in different experimental models and found safe up to 2000mg/kg body weight dose. The results provide an important basis for considering Shramahara Mahaakashaaya (SM) as an alternative medicine having anti-fatigue effects which can be further included in the sports medicine.
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