Abstract

 Objective: To demonstrate the changes in the urodynamic parameters of patients with posterior sacral neuromodulation and compare these changes to their pre-implantation parameters.
 Design: Observational, retrospective, comparative study of related variables. Urodynamic studies were performed on neurological patients who were candidates for posterior sacral neuromodulation (n=9). The candidates for a definitive neuromodulator underwent comparative statistical analysis using student´s t test for related samples. We evaluated on pressure-flow study: maximum flow, Pdet max, effectiveness of voiding, and compliance.
 Results: Statistically significant results were found in the urodynamic measurements at peak flow (Qmax p<0.002) and in changes in detrusor pressures (p<0.001), there were no statistically significant differences found in voiding effectiveness (p=0.02). 
 Limitations of the study-implication: A larger number of patients are needed to compare our results to international reports, and to adjust the time of implantation after neurological lesions, since our sample was very heterogeneous.
 Originality: There are no reports of sacral neuromodulation in Mexican patients exclusively with neurological disorders as described in other populations; this sample is being described as the largest population of neuromodulator carriers with neurourological diseases in Mexico.
 Conclusions: In spite of not finding differences in the effectiveness of voiding in our sample, this difference is of great clinical importance since it means a decrease in or suspension of clean intermittent catheterization, which is probably also reflected in the changes of the detrusor pressures that are within the limits and has benefits for the patient as protection of the upper urinary tract and a decrease of expenses.
Highlights
Lower Urinary tract dysfunction is a common condition, concomitant with previously diagnosed neurological patients
Urodynamic studies were performed on neurological patients who were candidates for posterior sacral neuromodulation (n=9)
In some other conditions, a bladder-sphincter neuromuscular dysfunction can be present prior to the neurological presentation, and it hints to looking after a neurological concomitant disease.[1] the upper urinary tract has sometimes already suffered some damage at the time of the urological/neurourological diagnosis
Summary
To demonstrate the changes in the urodynamic parameters of patients with posterior sacral neuromodulation and compare these changes to their pre-implantation parameters. Urodynamic studies were performed on neurological patients who were candidates for posterior sacral neuromodulation (n=9). Resultados: se encontraron resultados estadísticamente significativos en mediciones urodinámicas de flujo máximo (Qmax p
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