Abstract

Decision makers are increasingly concerned about both cost-effectiveness and affordability, resulting in the use of willingness-to-pay (WTP) and budget impact thresholds. The cost-effectiveness acceptability curve (CEAC) is widely used to summarize uncertainty in cost-effectiveness analysis (CEA) results. As CEAC ignores the resources necessary to fund the intervention and assumes a risk neutral attitude for decision makers, cost-effectiveness affordability curves (CEAFC), and since 2021, cost-effectiveness risk-aversion curves (CERAC) have been proposed to complement CEACs. We aim to assess whether the use of CEAFC has increased and where CERAC has been applied in economic evaluations of healthcare technologies.

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