Abstract

This study compared overall survival (OS) in patients receiving nivolumab + low-dose ipilimumab in CheckMate 142 versus patients in the real world (RW) receiving standard of care (SOC) therapy for second-line and later (2L+) microsatellite instability-high (MSI-H)/mismatch repair-deficient (dMMR) metastatic colorectal cancer (mCRC). CheckMate 142 is an ongoing, multi-cohort, nonrandomized phase 2 trial, and these results contextualize survival outcomes for Cohort 2 nivolumab + low-dose ipilimumab versus SOC.

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