Abstract
Although major conceptual paradigms underlying the EEG (i.e., differences between RCT-based efficacy and RWE-based effectiveness estimates) have been well described, few studies have quantitatively evaluated the magnitude of this gap for different cancer therapeutics. The objective of this TLR was to describe the methods and findings of studies that quantified EEG for cancer therapies and to critically synthesize this information to identify paths for future research.
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