Sa1663 Comparison of Clinical Outcomes Between Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection for Early Gastric Tumors by Quasi Randomization Using Propensity Score Matching Analysis

Abstract

Endoscopic mucosal resection (EMR) is an accepted technique for removal of early gastric tumors. The main drawback is the frequent need for piecemeal resection, with a risk of residual tumor and a reduced quality of histology, because en bloc resection reduces the risk of residual cancer. Endoscopic submucosal dissection (ESD) is known to overcome these disadvantages. Therefore, ESD seems to be more effective than EMR for curative resection of early gastric tumors and ESD is widely performed in japan as the initial therapy of early gastric tumors. However, randomized comparative study for the clinical outcomes between EMR and ESD was not reported. We evaluated the clinical outcomes of ESD compared with conventional EMR by quasi-randomization using propensity score matching analysis.