Abstract
It has been reported that alteration of intra-papillary capillary loop (IPCL) is important in detecting early esophageal squamous cell carcinoma (SCC). Also, brownish color change in the epithelia between each IPCL that we call “background coloration (BC)” has recently reported as an additional finding to differentiate SCC from non-neoplastic lesion. However, the cause of this phenomenon has not been identified. We applied anti-human Hemoglobin(Hb) antibody immuno-staining for both SCC and non-neoplastic lesions in order to illuminate the reason why cancer lesion can be positive for NBI, which is a specific wave length of Hb.
Published Version
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