Abstract
The upper gastrointestinal (GI) tract is one of the extracolonic sites for malignancy in patients with familial adenomatous polyposis (FAP). Gastric cancer causing the death of FAP patients in Japan has been reported to be 2.8% compared to 60.6% for colon cancer, 9.9% for desmoid disease and 5.6% for duodenal and ampullary cancer. Surveillance management for upper GI cancer can be difficult for clinicians involved in the follow-up care of FAP patients particularly with improved survival after prophylactic colectomy. There have only been a few studies conducted on upper GI diseases in FAP patients, however, so we investigated clinical outcomes of gastric polyps and neoplasms detected in such patients.
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