Abstract

SEmaglutide once-weekly randomized PRAgmatic Trial (SEPRA) (NCT03596450) is an ongoing, randomized, pragmatic trial comparing the effects of once-weekly subcutaneous semaglutide with other treatments for type 2 diabetes in routine clinical practice in the US. Traditionally, endpoints such as health care resource utilization and adherence are patient-reported in randomized trials. SEPRA utilized tokenization and linkage of study participants’ trial data to their claims data to support evaluation of supportive secondary endpoints. The objective of this project was to evaluate the overlap of participants with available claims data and compare baseline characteristics with the overall trial population.

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