Sa1387 A Randomised Trial Comparing Multiband Mucosectomy and ER-CAP for Endoscopic Piecemeal Resection of Early Squamous Neoplasia of the Esophagus

Abstract

and evaluated using SPSS software. Patients’ symptom status were assessed using Velanovich gastroesophageal health related quality of life (GERD-HRQL) scores. The Chi-square and Mann Witney-U tests were used for statistical analysis. Results: Of the 16 (59.3%) male and 11 (40.7%) female patients, mean age was 39.6 (range: 24-60) years and mean body mass index was 26.2 kg/m2. Groups were similar as to gender, age, and body mass index. None of the LARS cases were converted to open surgery. The one esophageal perforation observed in the SRS group was completely resolved by over-the-scope clipping (OTSC Ovesco Endoscopy AG. Tubingen, Germany). The duration of procedures for SRS and LARS were 89 and 47 minutes, respectively (p 0.05). The mean discharge time was longer for the LARS group (1.2 days) than for the SRS group (3 days, p 0.05); however—excluding the complicated patient in SRS group who stayed for 21 days—length of hospital stay was almost identical in both groups: 1.1 and 1.2 days, respectively (p 0.05). During the 6 months mean follow-up, bloating and dysphagia rates were similar between the groups (p 0.05). Rate of postoperative PPI usage was insignificantly higher in the SRS group (27.3%) than in the LARS (6.3%) (p 0.05). The mean GERD HRQL scores dropped from 29.3 to 4.1 and 24.8 to 8.9 in LARS and SRS groups, respectively (p 0.05). Conclusions: The short term results of SRS are promising. New generations of SRS, soon to be undergoing trials, and increasing experience may further improve results and decrease the untoward effects.