Sa1365 Natural History Following a Single Episode of Acute Pancreatitis

Abstract

Background & Aim: Patients with acute pancreatitis (AP), in particular severe cases, need appropriate nutrition management due to prolonged restriction of food intake and increased calorie requirement. However, little is known about the relationship between clinical condition and nutritional status in AP patients. Controlling nutritional status (CONUT), an easyto-use nutrition assessment system which scores laboratory data including serum albumin, total cholesterol level and peripheral blood lymphocyte count, has been considered to be efficient for early detection and continuous control of hospital undernutrition (Ignacio de Ulibarri J, et al., 2005). This study was aimed at investigating the usefulness of CONUT for treatment of AP patients. Methods: Of AP patients hospitalized at department of gastroenterology, Tohoku University Hospital from January 2003 to March 2012, 151 patients were evaluated for CONUT, retrospectively. AP patients were divided into two groups according to CONUT degree on admission, normal + light (CONUT-Low, CONUT score 0 ~ 4) and moderate + severe (CONUT-High, CONUT score 5 ~ 12). In each groups, the mortality, the risk of infectious complication, the rate of drainage or surgery, and length of hospital stay were examined. In addition, the changes of CONUT by nutritional intervention, such as enteral nutrition (EN) and total parenteral nutrition (TPN) were examined. Results: Normal, light, moderate and severe degree of CONUT were 14.6, 44.4, 29.1, and 11.9% of AP patients, respectively. The mortality of CONUT-High was 3.2%, but no patients died