Sa1147 Efficacy of Second-Look Endoscopy After Endoscopic Hemostasis in Acute Peptic Ulcer Bleeding : Risk Factor Analysis of Recurrent Bleeding

Abstract

G A A b st ra ct s stage IV. RESULTS: All pancreatic tumors were visualized by HIFU ultrasound monitor system. Treatment data in Stage III and IV were followed; mean tumor size was 31.8 vs 30.1 mm, mean treatment sessions: 2.6 vs 2.7 times, mean total treatment time: 2.7 vs 2.2 hours, mean total number of irradiation: 2801 vs 1769, respectively. There was no significant difference in treatment data between two groups. The effects of HIFU therapy in Stage III and IV were the following; the rate of complete tumor ablation was 87.5 vs 71.4%, the rate of symptom relief effect was 80 vs 56%, the effectiveness of primary lesion was CR:0, PR:2, SD:13, PD:1 vs CR:0, PR:2, SD:10, PD:2, and primary disease control rate (DCR) more than SD was 93.8% vs 78.6%. Mean survival time (MST) after HIFU therapy was 14.1 vs 7.2 month, respectively (p,0.01, p=0.0009). MST after diagnosis as PC was 32.4 vs 14.8 month, respectively (p,0.01, p=0.002). Combination therapy of HIFU with chemotherapy in Stage III was better result than common GEM single agent chemotherapy in our hospital. (MST: 14.9month). CONCLUSION: This study suggested that HIFU therapy has the potential of new method of combination therapy for non-metastatic PC.