Abstract

Cerebral maturation is a dynamic process that involves structural and functional maturation, initially linked to the expression of certain genes, endogenous generators of electrical activities and then dependent on peripheral information’s that contributes to Learning and the development of subsequent cortical functions. To address this maturation in children it is necessary to have non-invasive, non-ionizing tools. Thus, source imaging based on High-Resolution EEG together with optical imaging based on high-density functional Near Infrared Spectroscopy in the preterm infant allows to address the linear and non-linear dynamics, of the functional maturation of the structures and the neuronal mechanisms that gradually develop in the course of maturation as soon as 28 weeks Gestational Age.

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