Abstract
Neonatal seizures are the most common neurological emergency encountered in the neonatal intensive care unit (NICU). Clinical signs of seizures may be sparse or absent altogether in neonates and the true seizure burden is impossible to estimate without EEG monitoring. It is also essential to use EEG monitoring to measure the efficacy of any antiepileptic drug. Despite the need for neonatal EEG monitoring in the NICU, 24-h neonatal EEG interpretation expertise is rarely available. To address this need we developed the Algorithm for Neonatal Seizure Recognition or ANSeR. This presentation will describe the development of ANSeR including the lifecycle of training, testing, validation and bench side performance assessment. Finally, the results of a randomised controlled trial of this algorithm in eight NICUs across Europe will be presented.
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