Abstract
Blockchain applications in healthcare have grown rapidly. They include record-keeping, clinical trials, medical supply chains, patient monitoring, etc., where blockchain characteristics are needed to improve safety, privacy, and security. Blockchain technology is one of the most significant disruptive technologies today. However, Porru et al.1 reported that it lacks processes, tools, and techniques. Therefore, this paper provides a systematic framework for a secure and sustainable software engineering framework for healthcare blockchain applications (S3EF-HBCA). S3EF-HBCA is a significant contribution that includes requirements engineering for healthcare, business process modeling for healthcare, domain modeling for healthcare, a reference architecture for healthcare, and validation by a case study on electronic healthcare record management system (EHR), and simulation with business process modeling notation (BPMN) tools. The simulation shows it has taken 10.45 min to process 100 instances of real-time data and service requests. The overall result shows encouragement regarding process, tools, standards, and testing.
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