Abstract

BackgroundDeficits in social cognition and on social perception tasks are well studied and widely found in populations with schizophrenia. In addition, our work consistently replicates findings that individuals with schizophrenia report severe loneliness, significantly higher than healthy matches. Loneliness is a chronic, gnawing condition that induces distress and impedes life satisfaction and function across the spectrum of mental health. We also find social isolation impedes interpretation of social information and may lead to socio-perceptual deficits.The present study examines the effectiveness of a novel, adaptive virtual reality simulated social exposure training intervention (see Bekele et al, 2016) in both decreasing feelings of loneliness and improving social cognitive function in individuals with schizophrenia. We investigate baseline relationships between social isolation, loneliness and social cognition abilities, as well as pre to post intervention changes in function and subjective social well-being.MethodsFifteen medicated SZ outpatients completed 10 virtual reality social skills training sessions over the course of 5 weeks. Training sessions depicted three naturalistic social scenarios in which participants were instructed to complete 12 total social “missions” to obtain information from VR avatar characters. Prior to training and following the final training session, participants were assessed using the CogState Brief Schizophrenia Battery Social Emotional cognition task and rated loneliness using the UCLA Loneliness Scale. Independent raters conducted pre- and post-training clinical interviews to assess changes in participants’ levels of positive, negative, and overall psychiatric symptomsResultsGreater overall psychiatric symptoms were significantly correlated with higher levels of experienced loneliness, consistent with previous findings. There was a significant improvement in social emotional cognition accuracy, and a trend-level reduction in loneliness from pre-training to post-testing following social VR training.DiscussionPrevious research indicates that individuals higher on the psychosis spectrum perform worse at social cognition and social perception tasks. Our own research indicates that individuals higher on the psychosis spectrum also endorse higher levels of social distress via social isolation and loneliness. The present study attempts to enhance social cognitive and interpersonal abilities of individuals with schizophrenia while decreasing loneliness by strengthening social bonds and skills using a virtual reality training game. We find that following 10 sessions of VR social training, accuracy on measures of social cognition is improved significantly, however loneliness is reduced non-significantly. These initial results demonstrate potential feasibility of a novel VR social skills training game for improving social experience for patients with schizophrenia.

Highlights

  • Previous studies have shown that internalized stigma, i.e., the inner subjective experience of stigma resulting from applying negative stereotypes and stigmatizing attitudes to oneself, may impact negatively on schizophrenia patients’ quality of life, hope, and self-esteem and hinder the recovery process

  • Psychopathology was assessed by the Positive and Negative Syndrome Scale (PANSS), which was divided into five factors according to Wallwork et al.: positive, negative, disorganized/ concrete, excited, and depressed

  • A negative association was seen between premorbid social functioning and internalized stigma, whereas no correlation was found between premorbid school functioning and the Internalized Stigma of Mental Illness (ISMI) total score

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Summary

Poster Session III

S421 care program, COMBIMod; it combines several modules of therapeutic education and of cognitive remediation, after an individual assessment, clinical, cognitive and functional (quantitative and qualitative) of each patient. Methods: First, we described all the steps to enter COMBIMOD program since the global personalized assessments to the creation of an individualized program including cognitive remediation (Neurocognition and Socialcognition) and therapeutics education programs (MODip, MODen). We illustrated this program with patients verbatim. Discussion: These preliminary results confirm the importance of an integrative rehabilitation program including personalized assessments, motivation working, mixed cognitive remediation and psychoeducation programs. Silvia Pardeller*,1, Beatrice Frajo-Apor, Georg Kemmler, Annasara Meola, Fabienne Wartelsteiner, Wolfgang Fleischhacker, Alex Hofer1 1Medical University Innsbruck; 2University School of Medicine Federico II

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